Significant Role of Viruses in 0ral Squamous Cell Carcinoma Patients: A Review
نویسندگان
چکیده
منابع مشابه
Role of Brg1 in progression of esophageal squamous cell carcinoma
Objective(s): Epigenetic regulation of gene expression can be carried out through chromatin remodeling enzymes such as SWI/SNF. Brg1 also known as SMARCA4 is a catalytic subunit of SWI/SNF, which is necessary for MMPs expression. Matrix metalloproteinases (MMPs) are known as important player enzymes during tumor progression and metastasis. Aberrant epigenetic modification of chromatin should be...
متن کاملRole of EGFR Gene Polymorphisms in Oral Squamous Cell Carcinoma patients of Southeast of Iran: A Case-Control Study
Background: The decisive etiology of Oral squamous cell carcinoma (OSCC) is still ambiguous, but we recognize the contribution of genetic aberration and environmental agent due to OSCC initiation. In the current study, we elucidate the potential impact of EGFR gene polymorphisms in the risk of OSCC in the southeast of Iran. Methods: Forty-eight OSCC patients along with 100 normal volunteers w...
متن کاملRole of viruses in oral squamous cell carcinoma
The etiology of oral squamous cell carcinoma (OSCC) is complex and involves many factors. The most clearly defined risk factors are smoking and alcohol, which substantially increase the risk of oral SCC. However, despite this clear association, a substantial proportion of patients develop OSCC without exposure to them, emphasizing the role of other risk factors such as genetic susceptibility an...
متن کاملClinical Significance of Salivary Biomarkers in Oral Squamous Cell Carcinoma: A Review
Background and Aim: Oral squamous cell carcinoma (OSCC) accounts for approximately 3% of all cancers worldwide, and if diagnosed early, it has a five-year survival rate of around 85%; however, a late diagnosis may decrease the survival rate to 50%. Aberrant expression of several genes is associated with the hallmarks of OSCC including uncontrolled cell proliferation, poor differentiation, invas...
متن کاملCyclin D1 Expression in Patients with Laryngeal Squamous Cell Carcinoma
Background & Objective: Laryngeal squamous cell carcinoma (LSCC) is considered to be one of the most common cancers of the head and neck, accounting for roughly 90% of all malignant tumors of the larynx. To have a timely diagnosis for a better and practical therapy, molecular markers have to be investigated. The aim of this study was to determine the expression of Cyclin D1 (CD...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Modern Approaches in Dentistry and Oral Health Care
سال: 2019
ISSN: 2637-4692
DOI: 10.32474/madohc.2019.03.000180